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Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation

Cytosine methylation, predominantly of the CpG sequence in vertebrates, is one of the major epigenetic modifications crucially involved in the control of gene expression. Due to the difficulty of reconstituting site‐specifically methylated nucleosomal DNA at crystallization quality, most structural...

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Библиографические подробности
Опубликовано в: :FEBS Open Bio
Главные авторы: Fujii, Yoshifumi, Wakamori, Masatoshi, Umehara, Takashi, Yokoyama, Shigeyuki
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865653/
https://ncbi.nlm.nih.gov/pubmed/27419055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12064
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