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Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation

Cytosine methylation, predominantly of the CpG sequence in vertebrates, is one of the major epigenetic modifications crucially involved in the control of gene expression. Due to the difficulty of reconstituting site‐specifically methylated nucleosomal DNA at crystallization quality, most structural...

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Publicado en:FEBS Open Bio
Autores principales: Fujii, Yoshifumi, Wakamori, Masatoshi, Umehara, Takashi, Yokoyama, Shigeyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865653/
https://ncbi.nlm.nih.gov/pubmed/27419055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12064
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