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Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation

Cytosine methylation, predominantly of the CpG sequence in vertebrates, is one of the major epigenetic modifications crucially involved in the control of gene expression. Due to the difficulty of reconstituting site‐specifically methylated nucleosomal DNA at crystallization quality, most structural...

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Dades bibliogràfiques
Publicat a:FEBS Open Bio
Autors principals: Fujii, Yoshifumi, Wakamori, Masatoshi, Umehara, Takashi, Yokoyama, Shigeyuki
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865653/
https://ncbi.nlm.nih.gov/pubmed/27419055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12064
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