Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation

Phosphatidylinositol 4,5-biphosphate kinases (PIP5Ks) are critical regulators of T cell activation being the main enzymes involved in the synthesis of phosphatidylinositol 4,5-biphosphate (PIP2). PIP2 is indeed a pivotal regulator of the actin cytoskeleton, thus controlling T cell polarization and m...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Porciello, Nicla, Kunkl, Martina, Viola, Antonella, Tuosto, Loretta
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865508/
https://ncbi.nlm.nih.gov/pubmed/27242793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00186
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