CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter

CD28 is an important co-stimulatory receptor for T lymphocytes that, in humans, delivers TCR-independent signal leading to the up-regulation of pro-inflammatory cytokines. We have recently reported that CD28 autonomous signaling induces the expression of IL-17A in peripheral CD4(+) T lymphocytes fro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kunkl, Martina, Mastrogiovanni, Marta, Porciello, Nicla, Caristi, Silvana, Monteleone, Emanuele, Arcieri, Stefano, Tuosto, Loretta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491678/
https://ncbi.nlm.nih.gov/pubmed/31068940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00864
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