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The novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cells

Directional sensing, a process in which cells convert an external chemical gradient into internal signaling events, is essential in chemotaxis. We previously showed that a Rho GTPase, RacE, regulates gradient sensing in Dictyostelium cells. Here, using affinity purification and mass spectrometry, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Cell
Prif Awduron: Senoo, Hiroshi, Cai, Huaqing, Wang, Yu, Sesaki, Hiromi, Iijima, Miho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865317/
https://ncbi.nlm.nih.gov/pubmed/27009206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-11-0796
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