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The novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cells

Directional sensing, a process in which cells convert an external chemical gradient into internal signaling events, is essential in chemotaxis. We previously showed that a Rho GTPase, RacE, regulates gradient sensing in Dictyostelium cells. Here, using affinity purification and mass spectrometry, we...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Senoo, Hiroshi, Cai, Huaqing, Wang, Yu, Sesaki, Hiromi, Iijima, Miho
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865317/
https://ncbi.nlm.nih.gov/pubmed/27009206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-11-0796
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