Prevalence of Intrathecal Acyclovir Resistant Virus in Herpes Simplex Encephalitis Patients

Herpes simplex encephalitis (HSE) is a life-threatening complication of herpes simplex virus (HSV) infection. Acyclovir (ACV) is the antiviral treatment of choice, but may lead to emergence of ACV-resistant (ACV(R)) HSV due to mutations in the viral UL23 gene encoding for the ACV-targeted thymidine...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Mitterreiter, Johanna G., Titulaer, Maarten J., van Nierop, Gijsbert P., van Kampen, Jeroen J. A., Aron, Georgina I., Osterhaus, Albert D. M. E., Verjans, Georges M. G. M., Ouwendijk, Werner J. D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865163/
https://ncbi.nlm.nih.gov/pubmed/27171421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155531
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