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Prevalence of Intrathecal Acyclovir Resistant Virus in Herpes Simplex Encephalitis Patients

Herpes simplex encephalitis (HSE) is a life-threatening complication of herpes simplex virus (HSV) infection. Acyclovir (ACV) is the antiviral treatment of choice, but may lead to emergence of ACV-resistant (ACV(R)) HSV due to mutations in the viral UL23 gene encoding for the ACV-targeted thymidine...

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Bibliografiska uppgifter
I publikationen:	PLoS One
Huvudupphovsmän:	Mitterreiter, Johanna G., Titulaer, Maarten J., van Nierop, Gijsbert P., van Kampen, Jeroen J. A., Aron, Georgina I., Osterhaus, Albert D. M. E., Verjans, Georges M. G. M., Ouwendijk, Werner J. D.
Materialtyp:	Artigo
Språk:	Inglês
Publicerad:	Public Library of Science 2016
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4865163/ https://ncbi.nlm.nih.gov/pubmed/27171421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155531
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Prevalence of Intrathecal Acyclovir Resistant Virus in Herpes Simplex Encephalitis Patients

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