Validation and Optimization of an Ex Vivo Assay of Intestinal Mucosal Biopsies in Crohn’s Disease: Reflects Inflammation and Drug Effects

Crohn’s disease (CD) is a chronic illness demanding better therapeutics. The marketed biologics only benefit some patients or elicit diminishing effect over time. To complement the known methods in drug development and to obtain patient specific drug responses, we optimized and validated a known hum...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Vadstrup, Kasper, Galsgaard, Elisabeth Douglas, Gerwien, Jens, Vester-Andersen, Marianne Kajbæk, Pedersen, Julie Steen, Rasmussen, Julie, Neermark, Søren, Kiszka-Kanowitz, Marianne, Jensen, Teis, Bendtsen, Flemming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865152/
https://ncbi.nlm.nih.gov/pubmed/27171179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155335
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