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Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents

The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against M. tuberculosis, as well as eukaryotic cells....

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Kesicki, Edward A., Bailey, Mai A., Ovechkina, Yulia, Early, Julie V., Alling, Torey, Bowman, Julie, Zuniga, Edison S., Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua O., Parish, Tanya
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865136/
https://ncbi.nlm.nih.gov/pubmed/27171280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155209
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