Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents

The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against M. tuberculosis, as well as eukaryotic cells....

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Pubblicato in:PLoS One
Autori principali: Kesicki, Edward A., Bailey, Mai A., Ovechkina, Yulia, Early, Julie V., Alling, Torey, Bowman, Julie, Zuniga, Edison S., Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua O., Parish, Tanya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865136/
https://ncbi.nlm.nih.gov/pubmed/27171280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155209
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