PAI‐1, a target gene of miR‐143, regulates invasion and metastasis by upregulating MMP‐13 expression of human osteosarcoma

Despite recent improvements in the therapy for osteosarcoma, 30–40% of osteosarcoma patients die of this disease, mainly due to its lung metastasis. We have previously reported that intravenous injection of miR‐143 significantly suppresses lung metastasis of human osteosarcoma cells (143B) in a mous...

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Dades bibliogràfiques
Publicat a:Cancer Med
Autors principals: Hirahata, Mio, Osaki, Mitsuhiko, Kanda, Yusuke, Sugimoto, Yui, Yoshioka, Yusuke, Kosaka, Nobuyoshi, Takeshita, Fumitaka, Fujiwara, Tomohiro, Kawai, Akira, Ito, Hisao, Ochiya, Takahiro, Okada, Futoshi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864819/
https://ncbi.nlm.nih.gov/pubmed/26817521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.651
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