PAI‐1, a target gene of miR‐143, regulates invasion and metastasis by upregulating MMP‐13 expression of human osteosarcoma

Despite recent improvements in the therapy for osteosarcoma, 30–40% of osteosarcoma patients die of this disease, mainly due to its lung metastasis. We have previously reported that intravenous injection of miR‐143 significantly suppresses lung metastasis of human osteosarcoma cells (143B) in a mous...

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Detaylı Bibliyografya
Yayımlandı:Cancer Med
Asıl Yazarlar: Hirahata, Mio, Osaki, Mitsuhiko, Kanda, Yusuke, Sugimoto, Yui, Yoshioka, Yusuke, Kosaka, Nobuyoshi, Takeshita, Fumitaka, Fujiwara, Tomohiro, Kawai, Akira, Ito, Hisao, Ochiya, Takahiro, Okada, Futoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Cancer Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864819/
https://ncbi.nlm.nih.gov/pubmed/26817521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.651
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