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SK-216, a Novel Inhibitor of Plasminogen Activator Inhibitor-1, Suppresses Lung Metastasis of Human Osteosarcoma

Lung metastasis constitutes the leading cause of the death in patients with osteosarcoma. We have previously reported that plasminogen activator inhibitor-1 (PAI-1) regulates the invasion and lung metastasis of osteosarcoma cells in a mouse model and as well as in clinical samples. In the present st...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Tsuge, Minori, Osaki, Mitsuhiko, Sasaki, Ryo, Hirahata, Mio, Okada, Futoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877597/
https://ncbi.nlm.nih.gov/pubmed/29510576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030736
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