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Modifying the Mitochondrial Genome
Human mitochondria produce ATP and metabolites to support development and maintain cellular homeostasis. Mitochondria harbor multiple copies of a maternally-inherited, non-nuclear genome (mtDNA) that encodes for 13 subunit proteins of the respiratory chain. Mutations in mtDNA occur mainly in the 24...
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| Udgivet i: | Cell Metab |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4864607/ https://ncbi.nlm.nih.gov/pubmed/27166943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.04.004 |
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