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Modifying the Mitochondrial Genome

Human mitochondria produce ATP and metabolites to support development and maintain cellular homeostasis. Mitochondria harbor multiple copies of a maternally-inherited, non-nuclear genome (mtDNA) that encodes for 13 subunit proteins of the respiratory chain. Mutations in mtDNA occur mainly in the 24...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Patananan, Alexander N., Wu, Ting-Hsiang, Chiou, Pei-Yu, Teitell, Michael A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864607/
https://ncbi.nlm.nih.gov/pubmed/27166943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.04.004
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