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Calorie restriction regulates circadian clock gene expression through BMAL1 dependent and independent mechanisms
Feeding behavior, metabolism and circadian clocks are interlinked. Calorie restriction (CR) is a feeding paradigm known to extend longevity. We found that CR significantly affected the rhythms in the expression of circadian clock genes in mice on the mRNA and protein levels, suggesting that CR repro...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4864379/ https://ncbi.nlm.nih.gov/pubmed/27170536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25970 |
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