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Calorie restriction regulates circadian clock gene expression through BMAL1 dependent and independent mechanisms

Feeding behavior, metabolism and circadian clocks are interlinked. Calorie restriction (CR) is a feeding paradigm known to extend longevity. We found that CR significantly affected the rhythms in the expression of circadian clock genes in mice on the mRNA and protein levels, suggesting that CR repro...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Patel, Sonal A., Velingkaar, Nikkhil, Makwana, Kuldeep, Chaudhari, Amol, Kondratov, Roman
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864379/
https://ncbi.nlm.nih.gov/pubmed/27170536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25970
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