Circadian clocks govern calorie restriction–mediated life span extension through BMAL1- and IGF-1-dependent mechanisms

Calorie restriction (CR) increases longevity in many species by unknown mechanisms. The circadian clock was proposed as a potential mediator of CR. Deficiency of the core component of the circadian clock—transcriptional factor BMAL1 (brain and muscle ARNT [aryl hydrocarbon receptor nuclear transloca...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Patel, Sonal A., Chaudhari, Amol, Gupta, Richa, Velingkaar, Nikkhil, Kondratov, Roman V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2015
Konular:
Research Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799504/
https://ncbi.nlm.nih.gov/pubmed/26700733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-282475
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