EpCAM-based flow cytometry in cerebrospinal fluid greatly improves diagnostic accuracy of leptomeningeal metastases from epithelial tumors

BACKGROUND: Moderate diagnostic accuracy of MRI and initial cerebrospinal fluid (CSF) cytology analysis results in at least 10%–15% false negative diagnoses of leptomeningeal metastases (LM) of solid tumors, thus postponing start of therapy. The aim of this prospective clinical study was to determin...

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Publicado en:Neuro Oncol
Autores principales: Milojkovic Kerklaan, Bojana, Pluim, Dick, Bol, Mijke, Hofland, Ingrid, Westerga, Johan, van Tinteren, Harm, Beijnen, Jos H., Boogerd, Willem, Schellens, Jan H. M., Brandsma, Dieta
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Clinical Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864256/
https://ncbi.nlm.nih.gov/pubmed/26566655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov273
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