Extranuclear actions of the androgen receptor enhance glucose-stimulated insulin secretion in the male

Although men with testosterone deficiency are at increased risk of type 2 diabetes (T2D), previous studies have ignored the role of testosterone and the androgen receptor (AR) in pancreatic β–cells. We show that male mice lacking AR in β-cells (βARKO) exhibit decreased glucose-stimulated insulin sec...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Navarro, Guadalupe, Xu, Weiwei, Jacobson, David A., Wicksteed, Barton, Allard, Camille, Zhang, Guanyi, De Gendt, Karel, Kim, Sung Hoon, Wu, Hongju, Zhang, Haitao, Verhoeven, Guido, Katzenellenbogen, John A., Mauvais-Jarvis, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864089/
https://ncbi.nlm.nih.gov/pubmed/27133133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.03.015
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