Chemosensitizing effect of podophyllotoxin acetate on topoisomerase inhibitors leads to synergistic enhancement of lung cancer cell apoptosis

Podophyllotoxin acetate (PA) acts as a radiosensitizer against non-small cell lung cancer (NSCLC) in vitro and in vivo. In this study, we examined its potential role as a chemosensitizer in conjunction with the topoisomerase inhibitors etoposide (Eto) and camptothecin (Cpt). The effects of combinati...

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Publicat a:Int J Oncol
Autors principals: HONG, WAN GI, CHO, JEONG HYUN, HWANG, SANG-GU, LEE, EUNAH, LEE, JAESEOK, KIM, JONG-IL, UM, HONG-DUCK, PARK, JONG KUK
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863929/
https://ncbi.nlm.nih.gov/pubmed/27035096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3471
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