AMRI-59 functions as a radiosensitizer via peroxiredoxin I-targeted ROS accumulation and apoptotic cell death induction

Previously, we identified AMRI-59 as a specific pharmaceutical inhibitor of peroxiredoxin (PRX) I enzyme activity. In this study, we examined whether AMRI-59 acts as a radiosensitizer in non-small cell lung cancer cells using clonogenic assays. The intracellular mechanisms underlying the radiosensit...

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Pubblicato in:Oncotarget
Autori principali: Hong, Wan Gi, Kim, Ju Yeon, Cho, Jeong Hyun, Hwang, Sang-Gu, Song, Jie-Young, Lee, EunAh, Chang, Tong-Shin, Um, Hong-Duck, Park, Jong Kuk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768385/
https://ncbi.nlm.nih.gov/pubmed/29371968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23114
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