Efficacy and ototoxicity of different cyclodextrins in Niemann–Pick C disease

OBJECTIVE: Niemann–Pick type C (NPC) disease is a fatal, neurodegenerative, lysosomal storage disorder characterized by intracellular accumulation of unesterified cholesterol (UC) and other lipids. While its mechanism of action remains unresolved, administration of 2‐hydroxypropyl‐β‐cyclodextrin (HP...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Ann Clin Transl Neurol
Main Authors: Davidson, Cristin D., Fishman, Yonatan I., Puskás, István, Szemán, Julianna, Sohajda, Tamás, McCauliff, Leslie A., Sikora, Jakub, Storch, Judith, Vanier, Marie T., Szente, Lajos, Walkley, Steven U., Dobrenis, Kostantin
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863749/
https://ncbi.nlm.nih.gov/pubmed/27231706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.306
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares