A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1

3′-untranslated regions (UTRs) specify post-transcriptional fates of mammalian messenger RNAs (mRNAs), yet knowledge of the underlying sequences and mechanisms is largely incomplete. Here, we identify two related novel 3′ UTR motifs in mammals that specify transcript degradation. These motifs are in...

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Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Geissler, Rene, Simkin, Alfred, Floss, Doreen, Patel, Ravi, Fogarty, Elizabeth A., Scheller, Jürgen, Grimson, Andrew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863738/
https://ncbi.nlm.nih.gov/pubmed/27151978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.277392.116
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