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A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1
3′-untranslated regions (UTRs) specify post-transcriptional fates of mammalian messenger RNAs (mRNAs), yet knowledge of the underlying sequences and mechanisms is largely incomplete. Here, we identify two related novel 3′ UTR motifs in mammals that specify transcript degradation. These motifs are in...
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| Publié dans: | Genes Dev |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863738/ https://ncbi.nlm.nih.gov/pubmed/27151978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.277392.116 |
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