A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1

3′-untranslated regions (UTRs) specify post-transcriptional fates of mammalian messenger RNAs (mRNAs), yet knowledge of the underlying sequences and mechanisms is largely incomplete. Here, we identify two related novel 3′ UTR motifs in mammals that specify transcript degradation. These motifs are in...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Geissler, Rene, Simkin, Alfred, Floss, Doreen, Patel, Ravi, Fogarty, Elizabeth A., Scheller, Jürgen, Grimson, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2016
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863738/
https://ncbi.nlm.nih.gov/pubmed/27151978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.277392.116
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