A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1

3′-untranslated regions (UTRs) specify post-transcriptional fates of mammalian messenger RNAs (mRNAs), yet knowledge of the underlying sequences and mechanisms is largely incomplete. Here, we identify two related novel 3′ UTR motifs in mammals that specify transcript degradation. These motifs are in...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Geissler, Rene, Simkin, Alfred, Floss, Doreen, Patel, Ravi, Fogarty, Elizabeth A., Scheller, Jürgen, Grimson, Andrew
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863738/
https://ncbi.nlm.nih.gov/pubmed/27151978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.277392.116
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