Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine‐mediated immune protection

Influenza vaccination does not provide 100% protection from infection, partly due to antigenic drift of the haemagglutinin (HA) protein. Low serum antibody titres increase the risk of infection. To determine whether there were additional correlates of risk, we examined the relationship between human...

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Udgivet i:Immunology
Main Authors: DeDiego, Marta L., Anderson, Christopher S., Yang, Hongmei, Holden‐Wiltse, Jeanne, Fitzgerald, Theresa, Treanor, John. J., Topham, David J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863573/
https://ncbi.nlm.nih.gov/pubmed/26854888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12594
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