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Maximum Likelihood Estimation of Titer via a Power Family of Four-Parameter Logistic Model

For many laboratory assays, the readouts are presence or absence of a particular function, and the binary outcomes are correlated. The research interest is often focused on the estimation of titers, at which 50% positivity occurs. The classical approach by Reed and Muench (RM) assumes of a linear do...

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Bibliografske podrobnosti
izdano v:J Biopharm Stat
Main Authors: Yang, Hongmei, Holden-Wiltse, Jeanne, Topham, David J., Treanor, John
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158794/
https://ncbi.nlm.nih.gov/pubmed/28541821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2017.1333996
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