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Accelerated maximum likelihood parameter estimation for stochastic biochemical systems

BACKGROUND: A prerequisite for the mechanistic simulation of a biochemical system is detailed knowledge of its kinetic parameters. Despite recent experimental advances, the estimation of unknown parameter values from observed data is still a bottleneck for obtaining accurate simulation results. Many...

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Détails bibliographiques
Auteurs principaux: Daigle, Bernie J, Roh, Min K, Petzold, Linda R, Niemi, Jarad
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496601/
https://ncbi.nlm.nih.gov/pubmed/22548918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-68
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