Mouse and human CD8(+) CD28(low) regulatory T lymphocytes differentiate in the thymus

Regulatory T (Treg) lymphocytes play a central role in the control of immune responses and so maintain immune tolerance and homeostasis. In mice, expression of the CD8 co‐receptor and low levels of the co‐stimulatory molecule CD28 characterizes a Treg cell population that exerts potent suppressive f...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Vuddamalay, Yirajen, Attia, Mehdi, Vicente, Rita, Pomié, Céline, Enault, Geneviève, Leobon, Bertrand, Joffre, Olivier, Romagnoli, Paola, van Meerwijk, Joost P.M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863570/
https://ncbi.nlm.nih.gov/pubmed/26924728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12600
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