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Mouse and human CD8(+) CD28(low) regulatory T lymphocytes differentiate in the thymus

Regulatory T (Treg) lymphocytes play a central role in the control of immune responses and so maintain immune tolerance and homeostasis. In mice, expression of the CD8 co‐receptor and low levels of the co‐stimulatory molecule CD28 characterizes a Treg cell population that exerts potent suppressive f...

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Dettagli Bibliografici
Pubblicato in:Immunology
Autori principali: Vuddamalay, Yirajen, Attia, Mehdi, Vicente, Rita, Pomié, Céline, Enault, Geneviève, Leobon, Bertrand, Joffre, Olivier, Romagnoli, Paola, van Meerwijk, Joost P.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863570/
https://ncbi.nlm.nih.gov/pubmed/26924728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12600
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