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Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes

Thymus-derived regulatory T lymphocytes of CD4(+)CD25(+) phenotype regulate a large variety of beneficial and deleterious immune-responses and can inhibit lethal graft-versus-host disease in rodents. In vitro, CD4(+)CD25(+) T cells require specific MHC/peptide ligands for their activation, but once...

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Bibliografiset tiedot
Päätekijät: Joffre, Olivier, Gorsse, Nathalie, Romagnoli, Paola, Hudrisier, Denis, Van Meerwijk, Joost Pm
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516529/
https://ncbi.nlm.nih.gov/pubmed/14976053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-01-0005
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