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Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes
Thymus-derived regulatory T lymphocytes of CD4(+)CD25(+) phenotype regulate a large variety of beneficial and deleterious immune-responses and can inhibit lethal graft-versus-host disease in rodents. In vitro, CD4(+)CD25(+) T cells require specific MHC/peptide ligands for their activation, but once...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516529/ https://ncbi.nlm.nih.gov/pubmed/14976053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-01-0005 |
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