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Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors
To identify clinically important molecular subtypes of prostate cancer (PCa), we characterized the somatic landscape of aggressive tumors via deep, whole-genome sequencing. In our discovery set of ten tumor/normal subject pairs with Gleason scores of 8–10 at diagnosis, coordinated analysis of germli...
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Vydáno v: | Am J Hum Genet |
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Hlavní autoři: | , , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Elsevier
2016
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863563/ https://ncbi.nlm.nih.gov/pubmed/27087322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.03.003 |
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