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Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer
Studies of families who segregate BRCA2 mutations have found that men who carry disease-associated mutations have an increased risk of prostate cancer, particularly early-onset disease. A study of sporadic prostate cancer in the UK reported a prevalence of 2.3% for protein-truncating BRCA2 mutations...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360390/ https://ncbi.nlm.nih.gov/pubmed/17700570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603929 |
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