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Mapping the Germline and Somatic Mutation Interaction Landscape in Indolent and Aggressive Prostate Cancers

BACKGROUND: A majority of prostate cancers (PCas) are indolent and cause no harm even without treatment. However, a significant proportion of patients with PCa have aggressive tumors that progress rapidly to metastatic disease and are often lethal. PCa develops through somatic mutagenesis, but emerg...

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Опубликовано в: :J Oncol
Главные авторы: Mamidi, Tarun Karthik Kumar, Wu, Jiande, Hicks, Chindo
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878815/
https://ncbi.nlm.nih.gov/pubmed/31814827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4168784
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