Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass

The transforming growth factor-β (TGF-β) signaling network is a critical regulator of skeletal muscle mass and function and, thus, is an attractive therapeutic target for combating muscle disease, but the underlying mechanisms of action remain undetermined. We report that follistatin-based intervent...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Davey, Jonathan R., Watt, Kevin I., Parker, Benjamin L., Chaudhuri, Rima, Ryall, James G., Cunningham, Louise, Qian, Hongwei, Sartorelli, Vittorio, Sandri, Marco, Chamberlain, Jeffrey, James, David E., Gregorevic, Paul
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863241/
https://ncbi.nlm.nih.gov/pubmed/27182554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85477
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