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Phosphatases and Kinases Regulating CDC25 Activity in the Cell Cycle: Clinical Implications of CDC25 Overexpression and Potential Treatment Strategies

Alterations in the cell cycle regulatory genes result in uncontrolled cell proliferation leading to several disease conditions. Cyclin-dependent kinases (CDK) and their regulatory subunit, cyclins, are essential proteins in cell-cycle progression. The activity of CDK is regulated by a series of phos...

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Vydáno v:Mol Cell Biochem
Hlavní autoři: Sur, Swastika, Agrawal, Devendra K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862931/
https://ncbi.nlm.nih.gov/pubmed/27038604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-016-2693-2
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