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Roles of Greatwall Kinase in the Regulation of Cdc25 Phosphatase
We previously reported that immunodepletion of Greatwall kinase prevents Xenopus egg extracts from entering or maintaining M phase due to the accumulation of inhibitory phosphorylations on Thr14 and Tyr15 of Cdc2. M phase–promoting factor (MPF) in turn activates Greatwall, implying that Greatwall pa...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291418/ https://ncbi.nlm.nih.gov/pubmed/18199678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-11-1099 |
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