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The greatwall kinase is dominant over PKA in controlling the antagonistic function of ARPP19 in Xenopus oocytes

The small protein ARPP19 plays a dual role during oocyte meiosis resumption. In Xenopus, ARPP19 phosphorylation at S109 by PKA is necessary for maintaining oocytes arrested in prophase of the first meiotic division. Progesterone downregulates PKA, leading to the dephosphorylation of ARPP19 at S109....

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Foilsithe in:Cell Cycle
Main Authors: Dupré, Aude-Isabelle, Haccard, Olivier, Jessus, Catherine
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553396/
https://ncbi.nlm.nih.gov/pubmed/28722544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1338985
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