The greatwall kinase is dominant over PKA in controlling the antagonistic function of ARPP19 in Xenopus oocytes

The small protein ARPP19 plays a dual role during oocyte meiosis resumption. In Xenopus, ARPP19 phosphorylation at S109 by PKA is necessary for maintaining oocytes arrested in prophase of the first meiotic division. Progesterone downregulates PKA, leading to the dephosphorylation of ARPP19 at S109....

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Dupré, Aude-Isabelle, Haccard, Olivier, Jessus, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553396/
https://ncbi.nlm.nih.gov/pubmed/28722544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1338985
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