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The greatwall kinase is dominant over PKA in controlling the antagonistic function of ARPP19 in Xenopus oocytes
The small protein ARPP19 plays a dual role during oocyte meiosis resumption. In Xenopus, ARPP19 phosphorylation at S109 by PKA is necessary for maintaining oocytes arrested in prophase of the first meiotic division. Progesterone downregulates PKA, leading to the dephosphorylation of ARPP19 at S109....
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5553396/ https://ncbi.nlm.nih.gov/pubmed/28722544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1338985 |
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