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The phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes

Entry into mitosis or meiosis relies on the coordinated action of kinases and phosphatases that ultimately leads to the activation of Cyclin-B–Cdk1, also known as MPF for M-phase promoting factor. Vertebrate oocytes are blocked in prophase of the first meiotic division, an arrest that is tightly con...

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Autors principals: Dupré, Aude, Buffin, Eulalie, Roustan, Chloé, Nairn, Angus C., Jessus, Catherine, Haccard, Olivier
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757331/
https://ncbi.nlm.nih.gov/pubmed/23781026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.126599
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