Cell cycle-dependent Cdc25C phosphatase determines cell survival by regulating apoptosis signal-regulating kinase 1

Cdc25C (cell division cycle 25C) phosphatase triggers entry into mitosis in the cell cycle by dephosphorylating cyclin B-Cdk1. Cdc25C exhibits basal phosphatase activity during interphase and then becomes activated at the G(2)/M transition after hyperphosphorylation on multiple sites and dissociatio...

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Publicat a:Cell Death Differ
Autors principals: Cho, Y-C, Park, J E, Park, B C, Kim, J-H, Jeong, D G, Park, S G, Cho, S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563786/
https://ncbi.nlm.nih.gov/pubmed/25633196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.2
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