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Tissue Factor Residues That Modulate Magnesium-Dependent Rate Enhancements of the Tissue Factor/Factor VIIa Complex

The blood coagulation cascade is initiated when the cell-surface complex of factor VIIa (FVIIa, a trypsin-like serine protease) and tissue factor (TF, an integral-membrane protein) proteolytically activates factor X (FX). Both FVIIa and FX bind to membranes via their γ-carboxyglutamate-rich domains...

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Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Gajsiewicz, Joshua M., Nuzzio, Kristin M., Rienstra, Chad M., Morrissey, James H.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862878/
https://ncbi.nlm.nih.gov/pubmed/26169722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00608
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