Profoundly Reduced CD1c(+) Myeloid Dendritic Cell HLA-DR and CD86 Expression and Increased Tumor Necrosis Factor Production in Experimental Human Blood-Stage Malaria Infection

Dendritic cells (DCs) are sentinels of the immune system that uniquely prime naive cells and initiate adaptive immune responses. CD1c (BDCA-1) myeloid DCs (CD1c(+) mDCs) highly express HLA-DR, have a broad Toll-like receptor (TLR) repertoire, and secrete immune modulatory cytokines. To better unders...

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Foilsithe in:Infect Immun
Main Authors: Loughland, Jessica R., Minigo, Gabriela, Burel, Julie, Tipping, Peta E., Piera, Kim A., Amante, Fiona H., Engwerda, Christian R., Good, Michael F., Doolan, Denise L., Anstey, Nicholas M., McCarthy, James S., Woodberry, Tonia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
Ábhair:
Host Response and Inflammation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862702/
https://ncbi.nlm.nih.gov/pubmed/26902728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01522-15
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