Preserved Dendritic Cell HLA-DR Expression and Reduced Regulatory T Cell Activation in Asymptomatic Plasmodium falciparum and P. vivax Infection

Clinical illness with Plasmodium falciparum or Plasmodium vivax compromises the function of dendritic cells (DC) and expands regulatory T (Treg) cells. Individuals with asymptomatic parasitemia have clinical immunity, restricting parasite expansion and preventing clinical disease. The role of DC and...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Kho, Steven, Marfurt, Jutta, Noviyanti, Rintis, Kusuma, Andreas, Piera, Kim A., Burdam, Faustina H., Kenangalem, Enny, Lampah, Daniel A., Engwerda, Christian R., Poespoprodjo, Jeanne R., Price, Ric N., Anstey, Nicholas M., Minigo, Gabriela, Woodberry, Tonia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496614/
https://ncbi.nlm.nih.gov/pubmed/26034211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00226-15
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