Successful Therapy of Murine Visceral Leishmaniasis with Astrakurkurone, a Triterpene Isolated from the Mushroom Astraeus hygrometricus, Involves the Induction of Protective Cell-Mediated Immunity and TLR9

In our previous report, we showed that astrakurkurone, a triterpene isolated from the Indian mushroom Astraeus hygrometricus (Pers.) Morgan, induced reactive oxygen species, leading to apoptosis in Leishmania donovani promastigotes, and also was effective in inhibiting intracellular amastigotes at t...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Mallick, Suvadip, Dutta, Aritri, Chaudhuri, Ankur, Mukherjee, Debasri, Dey, Somaditya, Halder, Subhadra, Ghosh, Joydip, Mukherjee, Debarati, Sultana, Sirin Salma, Biswas, Gunjan, Lai, Tapan Kumar, Patra, Pradyumna, Sarkar, Indranil, Chakraborty, Sibani, Saha, Bhaskar, Acharya, Krishnendu, Pal, Chiranjib
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862535/
https://ncbi.nlm.nih.gov/pubmed/26883702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01943-15
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