Successful Therapy of Murine Visceral Leishmaniasis with Astrakurkurone, a Triterpene Isolated from the Mushroom Astraeus hygrometricus, Involves the Induction of Protective Cell-Mediated Immunity and TLR9

In our previous report, we showed that astrakurkurone, a triterpene isolated from the Indian mushroom Astraeus hygrometricus (Pers.) Morgan, induced reactive oxygen species, leading to apoptosis in Leishmania donovani promastigotes, and also was effective in inhibiting intracellular amastigotes at t...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Antimicrob Agents Chemother
المؤلفون الرئيسيون: Mallick, Suvadip, Dutta, Aritri, Chaudhuri, Ankur, Mukherjee, Debasri, Dey, Somaditya, Halder, Subhadra, Ghosh, Joydip, Mukherjee, Debarati, Sultana, Sirin Salma, Biswas, Gunjan, Lai, Tapan Kumar, Patra, Pradyumna, Sarkar, Indranil, Chakraborty, Sibani, Saha, Bhaskar, Acharya, Krishnendu, Pal, Chiranjib
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2016
الموضوعات:
Experimental Therapeutics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862535/
https://ncbi.nlm.nih.gov/pubmed/26883702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01943-15
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