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A First-in-Human Study To Assess the Safety and Pharmacokinetics of Monoclonal Antibodies against Human Cytomegalovirus in Healthy Volunteers

Human cytomegalovirus (HCMV) can cause significant disease in immunocompromised patients and treatment options are limited by toxicities. CSJ148 is a combination of two anti-HCMV human monoclonal antibodies (LJP538 and LJP539) that bind to and inhibit the function of viral HCMV glycoprotein B (gB) a...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Dole, Kiran, Segal, Florencia Pereyra, Feire, Adam, Magnusson, Baldur, Rondon, Juan C., Vemula, Janardhana, Yu, Jing, Pang, Yinuo, Pertel, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862512/
https://ncbi.nlm.nih.gov/pubmed/26926639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02698-15
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