In Vitro Characterization of Human Cytomegalovirus-Targeting Therapeutic Monoclonal Antibodies LJP538 and LJP539

Human cytomegalovirus (HCMV) infection is usually benign in healthy individuals but can cause life-threatening disease in those with compromised immune systems. Approved drugs available to treat HCMV disease, including ganciclovir, cidofovir, and foscarnet, have significant toxicities that limit the...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Patel, Hetalkumar D., Nikitin, Pavel, Gesner, Thomas, Lin, James J., Barkan, David T., Ciferri, Claudio, Carfi, Andrea, Akbarnejad Yazdi, Tahmineh, Skewes-Cox, Peter, Wiedmann, Brigitte, Jarousse, Nadine, Zhong, Weidong, Feire, Adam, Hebner, Christy M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958183/
https://ncbi.nlm.nih.gov/pubmed/27270290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00382-16
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