Longitudinal Analysis of the Effect of Inflammation on Voriconazole Trough Concentrations

Voriconazole (VCZ) exhibits great inter- and intrapatient variability. The latter variation cannot exclusively be explained by concomitant medications, liver disease or dysfunction, and genetic polymorphisms in cytochrome P450 2C19 (CYP2C19). We hypothesized that inflammatory response in patients un...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Encalada Ventura, M. A., van Wanrooy, M. J. P., Span, L. F. R., Rodgers, M. G. G., van den Heuvel, E. R., Uges, D. R. A., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J. W. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862487/
https://ncbi.nlm.nih.gov/pubmed/26883707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02830-15
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