Combined Bioinformatic and Rational Design Approach To Develop Antimicrobial Peptides against Mycobacterium tuberculosis

Drug-resistant pathogens are a growing problem, and novel strategies are needed to combat this threat. Among the most significant of these resistant pathogens is Mycobacterium tuberculosis, which is an unusually difficult microbial target due to its complex membrane. Here, we design peptides for spe...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Pearson, C. Seth, Kloos, Zachary, Murray, Brian, Tabe, Ebot, Gupta, Monica, Kwak, Jun Ha, Karande, Pankaj, McDonough, Kathleen A., Belfort, Georges
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862459/
https://ncbi.nlm.nih.gov/pubmed/26902758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00940-15
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